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Aldosterone

Serum Aldosterone Plasma Aldosterone Concentration (PAC)
Serum or EDTA plasma (posture and salt intake affect level; check local protocol) pmol/L

About this test

Mineralocorticoid produced by the adrenal zona glomerulosa. Regulates sodium retention and potassium excretion. Tested alongside plasma renin to calculate ARR.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs 70 – 950 Seated, normal sodium diet; varies significantly with posture and time of day

Clinical Interpretation

Low / Decreased
Low — hypoaldosteronism, Addison's disease, hyperkalaemia.
High / Increased
Elevated — primary hyperaldosteronism (Conn's syndrome), secondary hyperaldosteronism (heart failure, cirrhosis, renal artery stenosis).

Related Tests

Potassium Plasma Renin
Specimen
Serum or EDTA plasma (posture and salt intake affect level; check local protocol)
Reporting Unit
pmol/L
Category
⚗️ Endocrinology

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.