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Protein C Activity

Protein C PC Activity
Sodium citrate (blue top; off anticoagulation) %

About this test

Vitamin K-dependent natural anticoagulant. Activated by thrombin-thrombomodulin complex to inactivate FVa and FVIIIa. Deficiency causes inherited thrombophilia. Must not be tested on warfarin.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs 70 – 140 Adult functional (chromogenic)

Clinical Interpretation

Low / Decreased
Reduced — inherited Protein C deficiency (thrombophilia), liver disease, warfarin (vitamin K antagonism), DIC, sepsis.

Related Tests

Antithrombin III
Specimen
Sodium citrate (blue top; off anticoagulation)
Reporting Unit
%
Category
🩹 Coagulation

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.