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Antithrombin III

AT-III Antithrombin AT Activity
Sodium citrate (blue top) %

About this test

Natural anticoagulant inhibiting thrombin and FXa. Deficiency is a significant inherited thrombophilia risk factor. Also consumed in DIC and reduced in liver disease and nephrotic syndrome.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs 80 – 120 Adult functional (chromogenic or clot-based assay)

Clinical Interpretation

Low / Decreased
Reduced — inherited AT deficiency (thrombophilia), DIC, liver disease, nephrotic syndrome, L-asparaginase therapy, heparin therapy (modest reduction).

Related Tests

D-Dimer
Specimen
Sodium citrate (blue top)
Reporting Unit
%
Category
🩹 Coagulation

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.