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Thiamine

Vitamin B1 Thiamine Pyrophosphate TPP
EDTA whole blood (TPP preferred); avoid freeze-thaw nmol/L (whole blood TPP)

About this test

Essential for carbohydrate metabolism and neurological function. Deficiency causes Wernicke's encephalopathy and peripheral neuropathy (beriberi). Common in alcohol dependence and malnutrition.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs 70 – 180 Whole blood TPP; serum thiamine also measured (lower sensitivity)

Clinical Interpretation

Low / Decreased
Deficiency — Wernicke's encephalopathy (confusion, ophthalmoplegia, ataxia), Korsakoff's psychosis, wet or dry beriberi.

Related Tests

Magnesium Vitamin B12
Specimen
EDTA whole blood (TPP preferred); avoid freeze-thaw
Reporting Unit
nmol/L (whole blood TPP)
Category
💊 Vitamins

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.