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Anti-Jo-1

Anti-histidyl-tRNA Synthetase Jo-1 Antibody
Serum (SST) Positive/Negative

About this test

Myositis-specific antibody. Associated with anti-synthetase syndrome: myositis, interstitial lung disease, mechanic's hands, Raynaud's, arthritis.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs See notes Positive or Negative

Clinical Interpretation

Low / Decreased
Negative — anti-synthetase syndrome less likely (other MSAs exist).
High / Increased
Anti-synthetase syndrome, polymyositis, dermatomyositis with ILD.
Specimen
Serum (SST)
Reporting Unit
Positive/Negative
Category
🛡️ Immunology

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.