Home › Categories › Immunology › ANCA (cANCA)

ANCA (cANCA)

Cytoplasmic ANCA Proteinase-3 ANCA Anti-PR3 c-ANCA
Serum (SST) Titre / U/mL

About this test

Cytoplasmic pattern ANCA; usually directed against proteinase-3 (anti-PR3). Strongly associated with granulomatosis with polyangiitis (GPA/Wegener's).

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs See notes Positive or negative; positive requires anti-PR3 confirmation

Clinical Interpretation

Low / Decreased
Negative — GPA less likely.
High / Increased
Anti-PR3 positive — granulomatosis with polyangiitis (GPA). Disease activity tracking and relapse detection.
Specimen
Serum (SST)
Reporting Unit
Titre / U/mL
Category
🛡️ Immunology

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.