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Hepcidin

Serum Hepcidin Hepcidin-25
Serum (SST) µg/L (nmol/L)

About this test

Liver-derived peptide hormone that is the master regulator of iron homeostasis. Inhibits ferroportin-mediated iron export. Elevated in anaemia of inflammation; suppressed in iron deficiency.

Reference Ranges

Sex Age Range Notes
Female ≥ 18 yrs 17 – 286 Adult female
Male ≥ 18 yrs 29 – 254 Adult male (µg/L; highly assay-dependent)

Clinical Interpretation

Low / Decreased
Low hepcidin — iron deficiency, iron deficiency anaemia, hereditary haemochromatosis (HFE-related), hypoxia.
High / Increased
Elevated hepcidin — anaemia of chronic disease (infection, inflammation, malignancy), CKD.

Related Tests

Ferritin
Specimen
Serum (SST)
Reporting Unit
µg/L (nmol/L)
Category
⚙️ Iron Studies

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.