Home › Categories › Microbiology › EBV Heterophile Antibodies

EBV Heterophile Antibodies

Paul-Bunnell Test Monospot Test EBV Heterophile Test
Serum (SST) Positive/Negative

About this test

Rapid screening test for infectious mononucleosis caused by Epstein-Barr virus (EBV). Positive in ~85% of adolescent/adult cases; less sensitive in young children.

Reference Ranges

Sex Age Range Notes
All All ages See notes Negative or Positive

Clinical Interpretation

Low / Decreased
Negative — does not exclude EBV; check EBV-specific serology (VCA IgM/IgG, EBNA).
High / Increased
Positive — infectious mononucleosis (EBV). Avoid contact sports (splenomegaly risk), avoid amoxicillin (maculopapular rash).
Specimen
Serum (SST)
Reporting Unit
Positive/Negative
Category
🦠 Microbiology

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.