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Anti-Smooth Muscle Antibody

ASMA SMA Anti-Actin Antibody
Serum (SST) Titre (IIF)

About this test

Autoantibody against smooth muscle components (mainly actin). A key marker for autoimmune hepatitis type 1, often found alongside ANA.

Reference Ranges

Sex Age Range Notes
All ≥ 18 yrs See notes Positive (≥1:40) or Negative; titre reported

Clinical Interpretation

Low / Decreased
Negative makes AIH type 1 less likely (but ANA can be sole marker).
High / Increased
Autoimmune hepatitis type 1, PBC (lower titres), viral hepatitis.
Specimen
Serum (SST)
Reporting Unit
Titre (IIF)
Category
🛡️ Immunology

⚠ Clinical Note
Reference ranges are indicative. Always interpret results in the context of the individual patient and local laboratory reference intervals, which may vary.